Ayahuasca & changa

Ayahuasca and changa are psychedelic substances made by combining DMT (dimethyltryptamine) with MAO inhibitors (MAOIs), usually in the form of plants that contain them naturally.

Ayahuasca: 20–200 ml (equivalent to 50 mg DMT) Pharmahuasca: 150 mg moclobemide + 75 mg DMT
Changa: 60–100 mg (equivalent to 30–50 mg DMT)
Ayahuasca (swallowed): 4–6 hours
Pharmahuasca (swallowed): 3–4 hours
Changa (vaporized/smoked): 10–40 minutes
Acute lethality: ⦿⦾⦾⦾⦾ (Very low risk)
Long-term toxicity: ⦿⦾⦾⦾⦾ (Very low risk)
Dependence: ⦿⦾⦾⦾⦾ (Very low risk)
Cognitive problems: ⦿⦿⦾⦾⦾ (Low risk)
Undesirable events: ⦿⦿⦿⦾⦾ (Moderate risk)
Interactions: ⦿⦿⦿⦿⦾ (High risk)

Scroll down for the full risk profile.
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